%0 Journal Article
%T Arterial pressure variations as parameters of brain perfusion in response to central blood volume depletion and repletion
%A Anne-Sophie G. T. Bronzwaer
%A Berend E. Westerhof
%A Johannes J. van Lieshout
%J Frontiers in Physiology
%D 2014
%I Frontiers Media
%R 10.3389/fphys.2014.00157
%X Rationale: A critical reduction in central blood volume (CBV) is often characterized by hemodynamic instability. Restoration of a volume deficit may be established by goal-directed fluid therapy guided by respiration-related variation in systolic- and pulse pressure (SPV and PPV). Stroke volume index (SVI) serves as a surrogate end-point of a fluid challenge but tissue perfusion itself has not been addressed.
%K arterial pulse pressure
%K arterial systolic pressure
%K cerebrovascular circulation
%K fluid therapies
%K body fluids
%K head-up tilt
%K spontaneous breathing
%U http://www.frontiersin.org/Journal/10.3389/fphys.2014.00157/abstract