%0 Journal Article
%T Firing Behavior and Network Activity of Single Neurons in Human Epileptic Hypothalamic Hamartoma
%A Peter N. Steinmetz
%A John F. Kerrigan
%J Frontiers in Neurology
%D 2013
%I Frontiers Media
%R 10.3389/fneur.2013.00210
%X Objective: Human hypothalamic hamartomas (HH) are intrinsically epileptogenic and are associated with treatment-resistant gelastic seizures. The basic cellular mechanisms responsible for seizure onset within HH are unknown. We used intra-operative microwire recordings of single neuron activity to measure the spontaneous firing rate of neurons and the degree of functional connection between neurons within the tumor.
%K hypothalamic hamartoma
%K epilepsy
%K single unit
%K bursting
%K synchrony
%K microelectrode
%U http://www.frontiersin.org/Journal/10.3389/fneur.2013.00210/abstract