%0 Journal Article
%T Computational studies of DNA sequencing with solid-state nanopores: key issues and future prospects
%A Lijun Liang
%A Yaoquan Tu
%J Frontiers in Chemistry
%D 2014
%I Frontiers Media
%R 10.3389/fchem.2014.00005
%X Owing to the potential use for real personalized genome sequencing, DNA sequencing with solid-state nanopores has been investigated intensively in recent time. However, the area still confronts problems and challenges. In this work, we present a brief overview of computational studies of key issues in DNA sequencing with solid-state nanopores by addressing the progress made in the last few years. We also highlight future challenges and prospects for DNA sequencing using this technology.
%K solid-state nanopore
%K graphene nanopore
%K computer modeling
%K bio-nanotechnology
%K DNA sequencing
%K theory
%K molecular simulation
%U http://www.frontiersin.org/Journal/10.3389/fchem.2014.00005/abstract