%0 Journal Article
%T Stem cell transplantation improves aging-related diseases
%A Susumu Ikehara
%A Ming Li
%J Frontiers in Cell and Developmental Biology
%D 2014
%I Frontiers Media
%R 10.3389/fcell.2014.00016
%X Aging is a complex process of damage accumulation, and has been viewed as experimentally and medically intractable. The number of patients with age-associated diseases such as type 2 diabetes mellitus (T2DM), osteoporosis, Alzheimer¡¯s disease (AD), Parkinson¡¯s disease, atherosclerosis, and cancer has increased recently. Aging-related diseases are related to a deficiency of the immune system, which results from an aged thymus and bone marrow cells. Intra bone marrow-bone marrow transplantation (IBM-BMT) is a useful method to treat intractable diseases. This review summarizes findings that IBM-BMT can improve and treat aging-related diseases, including T2DM, osteoporosis and AD, in animal models.
%K Bone Marrow Transplantation
%K type 2 diabetes mellitus
%K oesteoporosis
%K Alzheimer's disease
%K aging-related diseases
%U http://www.frontiersin.org/Journal/10.3389/fcell.2014.00016/abstract