%0 Journal Article %T Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects %A Simon J. Schreiner %A Xinyang Liu %A Anton F. Gietl %A Michael Wyss %A Stefanie C. Steininger %A Valerie Treyer %A Andrea M. K£¿lin %A Alfred Buck %A Roger M. Nitsch %A Christoph Hock %A Paul G. Unschuld %J Frontiers in Aging Neuroscience %D 2014 %I Frontiers Media %R 10.3389/fnagi.2014.00240 %X Background: Accumulation of amyloid beta (A¦Â) may occur during healthy aging and is a risk factor for Alzheimer Disease (AD). While individual A¦Â-accumulation can be measured non-invasively using Pittsburgh Compund-B positron emission tomography (PiB-PET), Fluid-attenuated inversion recovery (FLAIR) is a Magnetic Resonance Imaging (MRI) sequence, capable of indicating heterogeneous age-related brain pathologies associated with tissue-edema. In the current study cognitively normal elderly subjects were investigated for regional correlation of PiB- and FLAIR intensity. %K PiB-PET %K MRI %K 7 Tesla %K amyloid beta %K FLAIR %K aging %U http://www.frontiersin.org/Journal/10.3389/fnagi.2014.00240/abstract