%0 Journal Article
%T Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects
%A Simon J. Schreiner
%A Xinyang Liu
%A Anton F. Gietl
%A Michael Wyss
%A Stefanie C. Steininger
%A Valerie Treyer
%A Andrea M. K£¿lin
%A Alfred Buck
%A Roger M. Nitsch
%A Christoph Hock
%A Paul G. Unschuld
%J Frontiers in Aging Neuroscience
%D 2014
%I Frontiers Media
%R 10.3389/fnagi.2014.00240
%X Background: Accumulation of amyloid beta (A¦Â) may occur during healthy aging and is a risk factor for Alzheimer Disease (AD). While individual A¦Â-accumulation can be measured non-invasively using Pittsburgh Compund-B positron emission tomography (PiB-PET), Fluid-attenuated inversion recovery (FLAIR) is a Magnetic Resonance Imaging (MRI) sequence, capable of indicating heterogeneous age-related brain pathologies associated with tissue-edema. In the current study cognitively normal elderly subjects were investigated for regional correlation of PiB- and FLAIR intensity.
%K PiB-PET
%K MRI
%K 7 Tesla
%K amyloid beta
%K FLAIR
%K aging
%U http://www.frontiersin.org/Journal/10.3389/fnagi.2014.00240/abstract