%0 Journal Article
%T Determination of Binding Parameters of Miramistin to Serum Albumin by the Bioluminescent Method
%A Nickolaj F. Starodub
%A Andrey M. Katsev
%A Elvira R. Abduramanova
%A Sergey L. Safronyuk
%A Marina V. Taran
%J Advances in Biological Chemistry
%P 331-338
%@ 2162-2191
%D 2014
%I Scientific Research Publishing
%R 10.4236/abc.2014.45038
%X Bioassay based on the luminescent bacteria was used as a new method for the determination of the kinetic constants of ligand binding to the complexion agent. Miramistin as the cationic surface-active antiseptic and serum blood albumin was taken as a model of interacting agent¡¯s. It was concluded that this approach might have a wide range for applications, namely, in all cases where the ligand is an inhibitor of bacterial luminescence and its complex dose not effect the intensity of this process.
%K Bioluminescent Inhibition Test
%K Miramistin
%K Albumin
%K Association Constants
%K Determination
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=48682