%0 Journal Article %T <i>In-Vitro</i> Effect of Sex Steroids on Mouse Melanoma (B16F10) Cell Growth %A Pandurangan Ramaraj %A James L. Cox %J CellBio %P 60-71 %@ 2325-7792 %D 2014 %I Scientific Research Publishing %R 10.4236/cellbio.2014.32007 %X
A battery of sex steroids were used to check their effect on mouse melanoma (B16F10) cell growth in-vitro. Progesterone and its synthetic receptor antagonist RU-486 showed maximum inhibition on in-vitro melanoma cell growth [1]. Further research work showed that the inhibition by progesterone was not a toxic, spurious or non-specific effect on mouse melanoma cell growth and the inhibition by progesterone was not mediated through progesterone receptor.
%K Sex Steroids %K B16 Mouse Melanoma %K MTT Growth Assay %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=46833