%0 Journal Article
%T Combined Effects of Blood Pressure and Aldosterone on Cardiac Left Ventricular Mass Index¡ªEthnic Differences between Kazakh, Uygur and Han Subjects
%A Masakatsu Ohta
%A Yuji Kasamaki
%A Yukio Ozawa
%A Atsushi Hirayama
%A Tomohiro Nakayama
%A Hiroshi Kawamura
%A Dilxat Himit
%A Masayoshi Soma
%A Yoichi Izumi
%J World Journal of Cardiovascular Diseases
%P 99-105
%@ 2164-5337
%D 2014
%I Scientific Research Publishing
%R 10.4236/wjcd.2014.43015
%X <p style=\"text-align:justify;\">
	<span style=\"font-size:10.0pt;font-family:;\" \"=\"\">Previous Background:
Hemodynamic factors</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">,</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> </span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">like</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> blood pressure</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">,</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> ha</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">ve</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> been established to be ma</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">jor
determinants of cardiac left ventricular structure. However, several factors
other than blood pressure to influence cardiac mass have been implicated. When
we did medical survey, cardiac left ventricular mass index (LVMI) of one ethnic
group that had higher blood pressure was found to be smaller than that of the
other ethnic groups with a lower blood pressure. Such contradicted data from
the present study w</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">ere</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> analyzed combining blood pressure, LVMI and
chemical parameters obtained from blood and urine. Methods: In a medical survey
conducted in Xinjiang, China, 279 people (65</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> </span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">-</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> </span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">70
years old) from three ethnic groups (Kazakh, Uygur and Han) from two separated
regions provided blood and urine samples and underwent echocardiography and
24-h ambulatory blood pressure monitoring (ABPM). Results: Systolic and
diastolic blood pressure obtained from ABPM and urinary sodium excretion values
were significantly higher in Kazakh than that in Uygur and Han. However, LVMI
in Kazakh was lower than that in other 2 groups. Plasma aldosterone
concentration (PAC) and plasma renin activity (PRA) were significantly lowest
in Kazakh. The values of LVMI in all ethnic groups were positively related to
both blood pressure and PAC. An inverse correlation was identified between PAC
and urinary sodium excretion value. Conclusion: Although higher blood pressure
in Kazakh subjects, their LVMI was lower than those of Uygur and Han, whose
blood pressure was lower than that in Kazakh. These
%K Left Ventricular Mass
%K Aldosterone
%K Blood Pressure
%K Salt Intake
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=43918