%0 Journal Article
%T Diffusion-Weighted MR Imaging of the Benign Hepatic Focal Lesions
%A Adel El-Badrawy
%A Germeen Albair Ashmallah
%A Ahmed Mohamed Tawfik
%A Sherif Abdelfattah
%A Manal Salah-Eldin
%A Emad Eldin Azmy
%A Amro Awad El-Karef
%A Ghada A. Salem
%A Omar Farouk
%J Open Journal of Radiology
%P 136-143
%@ 2164-3032
%D 2014
%I Scientific Research Publishing
%R 10.4236/ojrad.2014.41018
%X <p style=\"text-align:justify;\">
	Purpose: To
determine the role of diffusion weighted MR imaging and apparent diffusion coefficient (ADC) in benign hepatic focal lesions. Method and Materials:
This study included 47 patients (29 M, 18 F with mean age of 43 years) with benign hepatic focal lesions. They were cyst (n = 8), hemangioma (n = 23), abscess (n = 5), adenoma (n = 5), focal nodular
hyperplasia (n = 4) and nodular regenerative hyperplasia (n = 2). They underwent
routine MR imaging and diffusion MR weighted imaging using 1.5 tesla MR unit (Symphony-Siemens). Diffusion MR imaging was done
using spin echo type of single shot echo planar imaging (EPI) with b value of
0, 500 &amp; 1000 sec/mm2. The apparent diffusion coefficient (ADC)
map was reconstructed and ADC value was measured. The mean ADC values
correlated with histo-pathological results as well as follow-up imaging
results. Results: Adequate ADC
maps were obtained in 47 patients. The mean ADC values were 3.4 ¡À 0.12 ¡Á 10<sup>-3</sup> mm<sup>2</sup>/sec in cystic lesion, 2.23 ¡À 0.08 ¡Á 10<sup>-3</sup> mm<sup>2</sup>/sec in hemangioma, 1.94 ¡À 0.05 ¡Á 10<sup>-3</sup> mm<sup>2</sup>/sec
in abscess, 1.72 ¡À 0.07 ¡Á 10<sup>-3 </sup>in focal nodular hyperplasia, 1.65 ¡À 0.06 ¡Á 10<sup>-3</sup> mm<sup>2</sup>/sec
in adenoma, 1.62 ¡À 0.07 ¡Á 10<sup>-3</sup> mm<sup>2</sup>/sec in nodular regenerative
hyperplasia. The mean ADC values were significantly different within benign
hepatic focal lesions (P &lt; 0.001). The differences between the mean ADC
values of FNH, adenoma and NRH were not statistically significant (P &lt; 0.23). Conclusion: Diffusion weighted MR imaging is a new imaging
modality for diagnosis and characterization of different benign hepatic focal
lesions, particularly in patient with renal dysfunction.
</p>
%K Diffusion
%K MR Imaging
%K Apparent Diffusion Coefficient
%K Benign Hepatic Focal Lesion
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=43484