%0 Journal Article %T Five-Year Survivors of Non-Small Cell Lung Cancer Patients with Positive Pleural Lavage Cytology %A Masaki Tomita %A Takanori Ayabe %A Eiichi Chosa %A Kunihide Nakamura %J Advances in Lung Cancer %P 21-25 %@ 2169-2726 %D 2014 %I Scientific Research Publishing %R 10.4236/alc.2014.31003 %X
Background: The pleural lavage cytology (PLC) for non-small cell lung cancer (NSCLC) patients has been reported as a significant prognostic factor. The aim of this study is to clarify the clinicopathological characteristics of 5-year survivors of patients with positive PLC. Methods: Among 401 resected NSCLC patients, 30 (7.48%) patients with positive PLC were reviewed retrospectively. Results: Only 7 of 30 patients (23.3%) survived more than 5-year. There were no differences in age, gender, histology, pT status and pN status between 5-year survivors and non-survivors. On the other hand, the serum carcinoembryonic antigen (CEA) level was significantly higher in non-survivors. Among these 5-year survivors, 4 of 7 patients died of NSCLC recurrences more than 5 years after surgery. Remaining 3 patients survived without cancer recurrences. Interestingly these 3 survivors had not received any adjuvant therapies after surgery. Conclusion: None of the 5-year survivor with positive PLC had high serum CEA level. Furthermore 5-year survival did not equal to cure in NSCLC patients with positive PLC.
%K Pleural Lavage Cytology Positive %K Non-Small Cell Lung Cancer %K 5-Year Survivor %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=43134