%0 Journal Article
%T Antioxidants as effective remedies at hepatotoxic action of carbon tetrachloride
%A Karlen Hovnanyan
%A Vardan Mamikonyan
%A Anahit Margaryan
%A Kristine Sargsyan
%A Margarita Hovnanyan
%A Maria Karagyozyan
%A Konstantin Karageuzyan
%J Journal of Biophysical Chemistry
%P 1-4
%@ 2153-0378
%D 2014
%I Scientific Research Publishing
%R 10.4236/jbpc.2014.51001
%X <div align=\"justify\">
	The liver, as the central metabolic organ, plays an important role in metabolism of carbohydrates, lipids and proteins. In the environment, there are many hepatotoxic xenobiotics. CCl4 is a free radical toxic for organelles of hepatocytes. The presented work was studying the character of ultrastructural changes in CCl4-intoxicated hepatocytes as well as the tissue after treatment by grape seed extract (GSE), ¦Á-tocopherol (¦Á-T). As a result of cell bioremediation effect and reactions against corruptive factors, the liver has a high regeneration ability.
</div>
%K CCl4
%K GSE
%K ¦Á-Tocopherol
%K Ultrastructural Changes
%K Intoxicated Hepatocytes
%K Electron Microscopy
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=41999