%0 Journal Article
%T Differences in Acute Phase Reactants between Gout and Pseudogout
%A Clement E. Tagoe
%A Yasmin Raza
%J International Journal of Clinical Medicine
%P 13-19
%@ 2158-2882
%D 2013
%I Scientific Research Publishing
%R 10.4236/ijcm.2013.412A2003
%X <p class=\"MsoNormal\">
	<span lang=\"EN-US\" style=\"font-family:Verdana;\">Objectives:</span><span lang=\"EN-US\" style=\"font-family:Verdana;\"> To
define clinical differences in the acute phase response and serum acute phase
reactants between gout, pseudogout and crystal-induced arthritis in the
presence of non-articular infections (CAI).</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\" style=\"font-family:Verdana;\">Patients and Methods:</span><span lang=\"EN-US\"><span style=\"font-family:Verdana;\"> Eleven patients with definite gout, 12 patients with pseudogout and 5
patients with CIA were included in the study. </span><span style=\"font-family:Verdana;\">Results:</span><span style=\"font-family:Verdana;\"> The erythrocyte sedimentation rate (ESR) was significantly
different between gout (68.2 ¡À 49.9 mm/Hr) and CIA (113.8 ¡À 37.2 mm/Hr) but not
between gout and pseudogout (83.9 ¡À 45.6 mm/Hr) or between pseudogout and CIA.
The C-reactive protein (CRP) was significantly increased between gout (10.1 ¡À 7.9
mg/dL) and pseudogout (18.9 ¡À 9.8 mg/dL), gout and CIA (36.5 ¡À 12.4 mg/dL) as
well as between pseudogout and CIA. The peripheral white cell count was
significantly different between gout (9.27 ¡À 3.7 k/¦ÌL) and CIA (16.5 ¡À 6.8 k/¦ÌL),
and between pseudogout (8.9 ¡À 3.2 k/¦ÌL) and CIA. </span><span style=\"font-family:Verdana;\">Conclusions:</span><span style=\"font-family:Verdana;\"> Measurement of ESR and CRP are helpful in
crystal-induced arthritis. The CRP has more discriminating utility than the ESR
in distinguishing between gout, pseudogout and CIA. Peripheral wbc is most
useful for differentiating crystal-induced arthritis from CIA.</span></span>
</p>
%K Gout
%K Pseudogout
%K Crystal-Induced Arthritis
%K Acute Phase Reactants
%K C-Reactive Protein
%K Calcium  Pyrophosphate Dihydrate Deposition Disease
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=41313