%0 Journal Article
%T One-Pot Synthesis of Imidazolidine-2-Thiones, Hydantoins and Thiohydantoins under Solvent-Free and Grinding Conditions
%A Mohammad M. Ghanbari
%A Javad Safari
%A Zahra Roohi
%J Open Access Library Journal
%V 1
%N 7
%P 1-5
%@ 2333-9721
%D 2014
%I Open Access Library
%R 10.4236/oalib.1100705
%X A convenient, environmentally friendly and mild
green synthesis of imidazolidine-2-thiones, hydantoin and thiohydantoin
derivatives was developed by the one-pot reaction of benzils, urea or thiourea
derivatives, and strong base at with grinding. The key advantages are the short
reaction times, excellent yields, simple workup, and easy purification in the
solvent-free condition. The present method aimed to overcome the limitations
and drawbacks of the reported methods such as hard work-up, low yield, hazardous
solvent and long reaction time.
%K Green Synthesis
%K Imidazolidine-2-Thiones
%K Hydantoin
%K Thiohydantoin
%K Grinding
%K Solvent-Free
%U http://www.oalib.com/paper/3097933