%0 Journal Article
%T Envelope Glycoprotein Trimers as HIV-1 Vaccine Immunogens
%A Quentin J. Sattentau
%J Vaccines
%D 2013
%I MDPI AG
%R 10.3390/vaccines1040497
%X The HIV-1 envelope glycoprotein spike is the target of neutralizing antibody attack, and hence represents the only relevant viral antigen for antibody-based vaccine design. Various approaches have been attempted to recapitulate Env in membrane-anchored and soluble forms, and these will be discussed here in the context of recent successes and challenges still to be overcome.
%K HIV-1
%K vaccine
%K neutralizing antibodies
%K envelope glycoproteins
%K trimer
%U http://www.mdpi.com/2076-393X/1/4/497