%0 Journal Article
%T Simultaneous Determination of Dopamine, Serotonin and Ascorbic Acid at a Glassy Carbon Electrode Modified with Carbon-Spheres
%A Jianqing Zhou
%A Meili Sheng
%A Xueyue Jiang
%A Guozhi Wu
%A Feng Gao
%J Sensors
%D 2013
%I MDPI AG
%R 10.3390/s131014029
%X A novel glassy carbon electrode (GCE) modi£¿ed with carbon-spheres has been fabricated through a simple casting procedure. The modified GCE displays high selectivity and excellent electrochemical catalytic activities towards dopamine (DA), serotonin (5-HT), and ascorbic acid (AA). In the co-existence system, the peak separations between AA and DA, DA and 5-HT, and AA and 5-HT are large up to 230, 180, and 410 mV, respectively. Differential pulse voltammetry (DPV) has been employed to simultaneously detect DA, 5-HT, and AA, and the linear calibration curves for DA, 5-HT, and AA are obtained in the range of 20.0¨C150.0 ¦ÌM, 40.0¨C750.0 ¦ÌM and 300.0¨C2,000.0 ¦ÌM with detection limits (S/N = 3) of 2.0 ¦ÌM, 0.7 ¦ÌM and 0.6 ¦ÌM, respectively. The proposed electrode has been applied to detect DA, 5-HT, and AA in real samples using standard addition method with satisfactory results.
%K carbon-spheres
%K simultaneous determination
%K dopamine
%K ascorbic acid
%K serotonin
%U http://www.mdpi.com/1424-8220/13/10/14029