%0 Journal Article
%T General Intermediates for the Synthesis of 6-C-Alkylated DMDP-Related Natural Products
%A Mu-Hua Huang
%A Yi-Xian Li
%A Yue-Mei Jia
%A Chu-Yi Yu
%J Molecules
%D 2013
%I MDPI AG
%R 10.3390/molecules18066723
%X Protected L-homoDMDP en- 8 and its C-6 epimer en- 7 were prepared through two different pathways starting from the vinylpyrrolidine en- 9. Based on the NMR and X-ray analysis, the stereochemistry of homoDMDP at C-6 was confirmed to be consistent with reported data. Compounds en- 7 and en- 8 are general intermediates for the synthesis of a series of 6-C-alkylated DMDP-related natural products, such as broussonetine G, homoDMDP-7- O-apioside, homoDMDP-7- O-b-D-xyloside and so on.
%K homo-DMDP
%K broussonetine G
%K homoDMDP-7-O-apioside
%K glycosidase inhibitors
%K cyclic nitrones
%U http://www.mdpi.com/1420-3049/18/6/6723