%0 Journal Article
%T Flexibilisquinone, a New Anti-Inflammatory Quinone from the Cultured Soft Coral Sinularia flexibilis
%A Yu-Fang Lin
%A Chao-Ying Kuo
%A Zhi-Hong Wen
%A Yen-You Lin
%A Wei-Hsien Wang
%A Jui-Hsin Su
%A Jyh-Horng Sheu
%A Ping-Jyun Sung
%J Molecules
%D 2013
%I MDPI AG
%R 10.3390/molecules18078160
%X A new quinone derivative, flexibilisquinone ( 1), was isolated from the cultured soft coral Sinularia flexibilis, originally distributed in the waters of Taiwan. The structure of quinone 1 was established by extensive spectroscopic methods, particularly 1D and 2D NMR experiments. In the in vitro anti-inflammatory effects test, quinone 1 was found to significantly inhibit the accumulation of the pro-inflammatory iNOS and COX-2 proteins of the LPS-stimulated RAW264.7 macrophage cells.
%K flexibilisquinone
%K cultured soft coral
%K Sinularia flexibilis
%K anti-inflammatory
%K iNOS
%K COX-2
%U http://www.mdpi.com/1420-3049/18/7/8160