%0 Journal Article
%T Synthesis and SAR Studies of Praziquantel Derivatives with Activity against Schistosoma japonicum
%A Wen-Long Wang
%A Li-Jun Song
%A Xia Chen
%A Xu-Ren Yin
%A Wen-Hua Fan
%A Gu-Ping Wang
%A Chuan-Xin Yu
%A Bainian Feng
%J Molecules
%D 2013
%I MDPI AG
%R 10.3390/molecules18089163
%X The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described. Several of them showed better worm killing activity than praziquantel and could serve as leads for further optimization.
%K praziquantel derivatives
%K antischistosomal activity
%K Schistosoma japonicum
%K neglected tropical disease
%U http://www.mdpi.com/1420-3049/18/8/9163