%0 Journal Article
%T 3-Chloro-4-(5-methoxy-1H-indol-3-yl)cyclobut-3-ene-1,2-dione
%A Duc Ho¨¤ng Lande
%A Marleen Messal
%A Vincent Reimann
%A Caren Renger
%A Constanze Rurka
%A Jana Schoemaker
%A Nadin K. Schr£¿der
%A Johann Gr¨¹nefeld
%J Molbank
%D 2013
%I MDPI AG
%R 10.3390/M805
%X The indole ring system is a prominent partial structure of several protein kinase inhibitor families. The title compound is the first example of a 5-substituted indolyl squaryl chloride with free indole nitrogen. It has been synthesized by reaction of 5-methoxyindole with squaric acid dichloride in diethyl ether and its IR, 1H-NMR, 13C-NMR, MS, UV and HPLC data are presented. This compound may prove to be a rather useful building block for the preparation of various derivatives for biological studies.
%K Friedel-Crafts acylation
%K indole
%K squaric acid dichloride
%U http://www.mdpi.com/1422-8599/2013/3/M805