%0 Journal Article %T Efficacy of Extracorporeal Shock Wave Therapy for the Treatment of Chronic Pelvic Pain Syndrome: A Randomized, Controlled Trial %A Babak Vahdatpour %A Farshid Alizadeh %A Amir Moayednia %A Masoud Emadi %A Mohammad Hatef Khorami %A Saeid Haghdani %J ISRN Urology %D 2013 %R 10.1155/2013/972601 %X Objectives. To investigate the effectiveness of extracorporeal shock wave therapy (ESWT) for symptoms alleviation in chronic pelvic pain syndrome (CPPS). Materials and Methods. 40 patients with CPPS were randomly allocated into either the treatment or sham group. In the first group, patients were treated by ESWT once a week for 4 weeks by a defined protocol. In the sham group, the same protocol was applied but with the probe being turned off. The follow-up assessments were done at 1, 2, 3, and 12 weeks by Visual Analogue Scale (VAS) for pain and NIH-developed Chronic Prostatitis Symptom Index (NIH-CPSI). Results. Pain domain scores at follow-up points in both treatment and sham groups were reduced, more so in the treatment group, which were significant at weeks 2, 3, and 12. Urinary scores became significantly different at weeks 3 and 12. Also, quality of life (QOL) and total NIH-CPSI scores at all four follow-up time points reduced more significantly in the treatment group as compared to the sham group. Noticeably, at week 12 a slight deterioration in all variables was observed compared to the first 3 weeks of the treatment period. Conclusions. our findings confirmed ESWT therapy as a safe and effective method in CPPS in short term. 1. Introduction Chronic pelvic pain syndrome (CPPS) is a frequent outpatient urological diagnosis [1]. The incidence is increasing, being reported to be around 15% [2¨C4]. Symptoms of CPPS are urinary and erectile dysfunctions and pain in the prostate, perineal, inguinal, scrotal, and suprapubic regions, lasting for at least 3 of the previous 6 months [5¨C7]. The quality of life (QOL) is also disturbed as the result of urinary and erectile dysfunctions [8, 9]. Greater pain and urinary symptoms are associated with worse QOL [10, 11]. The pathophysiology of CPPS has not yet been completely explained. Psychiatric and somatic factors possibly play roles; however, no infection or bacterial pathogen has been detected yet [12]. Moreover, myofascial pain syndrome along with a neurological component has been associated with dysfunctional effects of this disease [13¨C15]. Medical therapies such as analgesics, anti-inflammatory agents, antibiotics, -receptor blockers, and 5 -reductase inhibitors have been used as single or combination therapy with variable success rates [7, 16, 17]. There are also some alternative therapies that have been introduced such as physiotherapy, trigger-point massage, electromagnetic treatment, acupuncture, rectal massage, hyperthermia, thermotherapy, balloon dilatation, laser coagulation, invasive %U http://www.hindawi.com/journals/isrn.urology/2013/972601/