%0 Journal Article
%T The Association between Alcohol Dependence and Depression before and after Treatment for Alcohol Dependence
%A Mary W. Kuria
%A David M. Ndetei
%A Isodore S. Obot
%A Lincoln I. Khasakhala
%A Betty M. Bagaka
%A Margaret N. Mbugua
%A Judy Kamau
%J ISRN Psychiatry
%D 2012
%R 10.5402/2012/482802
%X The presence of depression in alcohol-dependent persons is likely to influence treatment process and outcomes. Identification of depression is important though not every depressed alcohol-dependent person requires treatment with antidepressants. Understanding the association between depression and alcohol dependence is essential for proper management of alcohol dependence. Objectives. To determine the prevalence of depression among alcohol-dependent persons before and after alcohol detoxification and rehabilitation. Design. Clinical trial with pre-/postmeasurements. Method. The CIDI and WHO-ASSIST were administered to 188 alcohol-dependent persons at intake and after six months. A researcher-designed sociodemographic questionnaire was also administered at intake. Results. The prevalence of depression among alcohol-dependent persons is high (63.8%) with a significant association between depression and the mean AUDIT score. At posttest, depressed participants had a statistically significant craving for alcohol. Conclusion. Alcohol dependence is associated with major depression. 1. Introduction The prevalence of comorbidity of depression and alcohol use disorders (AUD) has been demonstrated in a number of researches [1¨C4]. Depression in an alcohol-dependent person has been reported to not only lower the resolve to resisting alcohol use, but may also lead to use of alcohol to relive the depressive symptoms [5, 6]. It is important to understand the significance of cooccurrence of depression and alcohol use disorders since this may explain why majority of cases relapse after treatment for alcohol dependence [5, 6]. In addition it may explain why antidepressants have been shown to moderately benefit patients with both depression and alcohol use disorders [7]. In Kenya a study by Ndetei et al. showed that there was positive correlation between major depressive illness, panic disorder, and alcohol abuse among patients admitted at the main referral psychiatric hospital [8]. Although the cooccurrence of depression and alcohol use disorders has been confirmed by several studies, the relationship between the two disorders has been difficult to describe [9]. This cooccurrence is at prevalence rate of 16%¨C68% [10]. Studies have attempted to differentiate between depressed and nondepressed alcohol-dependent persons with particular focus on the participantĄ¯s level of alcohol dependence, demographic characteristics, or illness-related variables. It has been shown that depression is more related to the current alcohol drinking episode than lifetime diagnosis of depression
%U http://www.hindawi.com/journals/isrn.psychiatry/2012/482802/