%0 Journal Article %T Pedicle-Screw-Based Dynamic Systems and Degenerative Lumbar Diseases: Biomechanical and Clinical Experiences of Dynamic Fusion with Isobar TTL %A C¨¦dric Barrey %A Gilles Perrin %A Sabina Champain %J ISRN Orthopedics %D 2013 %R 10.1155/2013/183702 %X Dynamic systems in the lumbar spine are believed to reduce main fusion drawbacks such as pseudarthrosis, bone rarefaction, and mechanical failure. Compared to fusion achieved with rigid constructs, biomechanical studies underlined some advantages of dynamic instrumentation including increased load sharing between the instrumentation and interbody bone graft and stresses reduction at bone-to-screw interface. These advantages may result in increased fusion rates, limitation of bone rarefaction, and reduction of mechanical complications with the ultimate objective to reduce reoperations rates. However published clinical evidence for dynamic systems remains limited. In addition to providing biomechanical evaluation of a pedicle-screw-based dynamic system, the present study offers a long-term (average 10.2 years) insight view of the clinical outcomes of 18 patients treated by fusion with dynamic systems for degenerative lumbar spine diseases. The findings outline significant and stable symptoms relief, absence of implant-related complications, no revision surgery, and few adjacent segment degenerative changes. In spite of sample limitations, this is the first long-term report of outcomes of dynamic fusion that opens an interesting perspective for clinical outcomes of dynamic systems that need to be explored at larger scale. 1. Introduction Dynamic instrumentation for fusion has been introduced since the 1990s to address the adverse effects of traditional spinal fusion observed with rigid instrumentation: pseudarthrosis, bone rarefaction, and mechanical failure [1, 2]. Some authors suggested that eliminating mechanical loads on an interbody bone graft may result in negative bone remodeling, pseudarthrosis, and osteoporosis [3¨C6]. This ¡°stress shielding¡± phenomenon at the disk space level may result from the excessive stiffness of traditional rigid instrumentation. Reducing the stiffness of the instrumentation, pedicle-screw-based posterior dynamic systems (PDSs) allow for load sharing between the instrumentation and the functional spine unit (FSU) at the instrumented level(s). Using a finite element model of the lumbar spine, several authors demonstrated that posterior dynamic instrumentation, compared to rigid instrumentation, increases the amount of load transmission through the anterior column and the interbody bone graft thus avoiding stress shielding phenomenon. This may favor osteogenesis and enhance interbody fusion in accordance with Wolff¡¯s Law according to which the bone will adapt to the loads it is placed under; that is, the structure and shape of %U http://www.hindawi.com/journals/isrn.orthopedics/2013/183702/