%0 Journal Article %T Nanobiosensors: Concepts and Variations %A Parth Malik %A Varun Katyal %A Vibhuti Malik %A Archana Asatkar %A Gajendra Inwati %A Tapan K. Mukherjee %J ISRN Nanomaterials %D 2013 %R 10.1155/2013/327435 %X Biosensing has been one of the hottest topic attracting scientific minds since long back. It is so as biological entities are very complex and are directly associated with the existence of a healthy environment. The design of biosensors also has witnessed significant changes in the recent past. Biosensors for applications as diverse as food quality estimation, environmental monitoring, and diagnosis of clinical and metabolic complications have come to the fore. Nanotechnology has bestowed some highly exciting ingredients for the improvement of sensing phenomenon. The use of diverse nanomaterials ranging from nanoparticles, nanotubes, nanorods, and nanowires has enabled faster detection and its reproducibility in a much better way. The unique properties of nanomaterials such as high electrical conductivity, better shock bearing ability, and the sensitive responses such as piezoelectric and versatile color based detection mechanisms are only the results of congregation of nanomaterial properties. This paper highlights the different types of biosensors based on different types of nanomaterials and their developmental and implicational aspects. 1. Introduction Sensing the biological responses has assumed great significance in the current scenario of ever dynamic environmental developments and corresponding altered homeostatic happenings occurring at both in vivo as well as ex vivo levels. The analysis of behavior of the ever changing materials has assumed great significance in areas like pharmaceutical diagnosis, screening food quality, and environmental applications. In this reference, the development of efficient biosensors which can analyze the minutest details of the biological interactions even at a very small scale and with extreme precision and maximum ever possible sensitivities deserves urgent attention [1]. A key component of the biosensing is the transduction mechanisms which are responsible for converting the responses of bioanalyte interactions in an identifiable and reproducible manner using the conversion of specific biochemical reaction energy into an electrical form through the use of transduction mechanisms. Nanomaterials can be wonderful incumbents in this dimension as they have high surface area to volume ratios which allow the surface to be used in a better and far more diversely functional manner. Moreover, their electromechanical properties are the wonderful assets for the biosensor technology. Nanostructural wonders provided by nanotechnology have revolutionized the happenings in the domain of molecular biology which have provided an %U http://www.hindawi.com/journals/isrn.nanomaterials/2013/327435/