%0 Journal Article
%T Tissue Reactions to Various Suture Materials Used in Oral Surgical Interventions
%A Fawad Javed
%A Mansour Al-Askar
%A Khalid Almas
%A Georgios E. Romanos
%A Khalid Al-Hezaimi
%J ISRN Dentistry
%D 2012
%R 10.5402/2012/762095
%X A variety of suture materials are available for primary wound closure following oral surgical procedures. The aim was to review the tissue reactions to the various suture materials used in oral surgical interventions. Databases were searched using the following keywords: cotton, nylon, polyglecaprone 25, polytetrafluoroethylene (ePTFE), Polyglactin 910, polyglycolic acid (PGA), polylactic acid, silk, surgery, suture, and tissue reaction. Articles published only in English language were included. Seventeen studies were included. Two studies reported that polyglecaprone 25 had positive effects on wound-healing as compared to silk. Six studies reported that silk elicits more intense tissue inflammatory response and delayed wound healing as compared to other suture materials (including ePTFE, polyglecaprone-25, PGA, and nylon). Polyglactin 910 sutures were associated with the development of stitch abscess in one clinical study. Eight studies reported that tissue reactions are minimal with nylon sutures. Tissue reactions to suture materials used for oral surgical interventions may vary depending on the surface properties and bacterial adherence properties of the material. 1. Introduction Most oral surgical interventions require primary wound closure using a previously raised flap. For this purpose, a variety of suture materials are available which may be classified upon their origin (organic and synthetic) or according to their durability in host tissues (absorbable and nonabsorbable) [1, 2]. The essential features of suture material include (1) knot safety, (2) stretch capacity, (3) tissue reactivity, and (4) wound safety. Besides the adopted surgical and suturing technique, the choice of suture material may also influence the healing of the incised soft tissues [1¨C3]. In their study, Vastardis and Yukna [4] reported three case reports of complications after the use of an subepithelial connective tissue graft where an abscess occurred following the initial healing phase. This study [4] concluded that a stitch abscess or reaction to the suture material used for the submerged sutures could be a possible cause of the abscesses. Thus the selection of the suture material should be brought under consideration during treatment planning for oral surgical interventions. Tissue reaction is reflected through an inflammatory response, which develops during the first two to seven days after suturing the tissue [1¨C3]. Several studies published over the past four decades have reported that synthetic materials exhibit a superior behavior to oral tissues in terms of tissue
%U http://www.hindawi.com/journals/isrn.dentistry/2012/762095/