%0 Journal Article
%T Metastasis of a Prostatic Carcinoma along an Omental Graft in a Dog
%A Terry M. Jacobs
%A Bruce R. Hoppe
%A Cathy E. Poehlmann
%A Marie E. Pinkerton
%A Milan Milovancev
%J Case Reports in Veterinary Medicine
%D 2013
%I Hindawi Publishing Corporation
%R 10.1155/2013/141094
%X An 11-year-old male American Bulldog was presented for hematuria and tenesmus. It had been treated for chronic bacterial prostatitis with abscessation two years earlier and underwent castration and a prostatic omentalization procedure. There was no histologic evidence of prostatic neoplasia at that time. On physical examination, an enlarged prostate was found by rectal palpation, and it was characterized with ultrasonography and computed tomography. Surgical biopsies were obtained, and histopathology identified prostatic adenocarcinoma. It received carprofen and mitoxantrone chemotherapy in addition to palliative radiation therapy; it was euthanized six weeks later due to a progression of clinical signs. Necropsy findings included marked localized expansion of the prostatic tumor and dissemination of prostatic carcinoma cells throughout the peritoneal cavity along the omental graft with infiltration onto the serosal surfaces of most abdominal viscera and fat. This case represents a previously unreported potential complication of the omentalization procedure wherein carcinoma cells from a prostatic tumor that independently arose after omentalization may have metastasized along the surgically created omental graft. 1. Introduction The surgical treatment of canine prostate abscesses was revolutionized by the application of an intracapsular prostatic omentalization technique first reported by White and Williams in 1995 [1]. In this procedure, an omental graft is tunneled through the parenchyma of the prostate after digitally breaking down any loculated abscesses and is sutured to the prostate. The omentum provides vascular and lymphatic drainage to cavitated sites of infection within the prostate gland. Along with systemic antibiotic therapy, prostatic omentalization has enabled the successful management of many refractory cases of prostatitis in dogs. No long-term complications have been reported with this technique. Prostatic carcinoma in dogs is generally an aggressive malignancy characterized by local invasiveness and early metastasis to regional lymph nodes, liver, lung, and bone [2¨C5]. Clinical signs are variable but typically include hematuria, stranguria, urinary incontinence, tenesmus, and pain, which may be localized if skeletal metastasis has occurred. The presence of an enlarged prostate in a neutered male dog may indicate malignancy; however, the prostate is not enlarged in all cases of prostatic carcinoma [4]. Radiography, ultrasonography, and computed tomography (CT) are useful imaging techniques to assess the prostate for the disease and to
%U http://www.hindawi.com/journals/crivem/2013/141094/