%0 Journal Article
%T Biopsy with the New Essen Biopsy Forceps
%A Peter G. Traine
%A Katharina J. E. Schedler
%A Mariuccia G. S. Brusa
%A Eduardo B. Rodrigues
%J Case Reports in Ophthalmological Medicine
%D 2013
%I Hindawi Publishing Corporation
%R 10.1155/2013/413259
%X Purpose. To present initial experience with a novel biopsy method, the Essen biopsy forceps. Therefore, two patients with diagnostic suspicion of uveal melanoma underwent biopsy for histopathological confirmation. Case Presentation. Two patients presented with painless unilateral vision reduction. Ultrasound revealed the diagnostic suspicion of uveal melanoma. Therefore, biopsy with the Essen biopsy forceps using a sutureless 23-gauge three-port vitrectomy system was performed. The specimens were then submitted to a pathologist and processed. Histopathology of the obtained specimen confirmed the diagnostic suspicion of choroid melanoma in both patients. Conclusion. Essen biopsy forceps is a very practicable alternative method to the FNAB, allowing a combined histopathological and immunohistochemical examination for achieving high diagnostic accuracy at minimal risk. 1. Introduction Intraocular tumors can be diagnosed with clinical exams and additional radiologic tests. In some cases, such as amelanotic melanoma, it is necessary to perform intraocular biopsy. Mostly used method of biopsy is fine-needle aspiration biopsy (FNAB) [1]. The purpose of this paper is to present initial experience with the novel biopsy method, the Essen biopsy forceps (Figure 2(a), Dutch Ophthalmic Research Center, Zuidland, The Netherlands). With this very practicable method, feasible even in smaller medical institutions without direct access to a pathologic department, it is possible to obtain tissue allowing a combined histopathological and immunohistochemical examination. 2. Case Reports 2.1. Case 1 A twenty-three-year old female presented with progressive painless vision reduction on the right eye for 6 months. Her medical, ophthalmological, and family history was unremarkable. She was able to perceive shapes in the right eye and visual acuity was 20/20 in the left eye. Intraocular pressure was 14 and 17£¿mmHg. Fundoscopy of the right eye showed a complete retinal detachment and a tumoral mass temporal-inferior-nasal (Figure 1(a)). Transpalpebral ultrasonography showed a 17 15 10.5£¿mm measuring mass with a positive kappa angle (Figure 1(b)). Suspecting uveal melanoma, the patient requested histopathological confirmation before undergoing enucleation. Biopsy with the Essen biopsy forceps using a sutureless 23-gauge three-port vitrectomy system was performed. The specimen obtained measured 2 1£¿mm, and histopathological section showed a fragment of collagenous connective tissue permeated by melanophages and, separate from this, a loose grouping of atypical, polymorphic cells
%U http://www.hindawi.com/journals/criopm/2013/413259/