%0 Journal Article %T Orthokeratinized Odontogenic Cyst: A Report of Three Clinical Cases %A Mar¨ªa del Carmen Gonz¨¢lez Galv¨¢n %A Abel Garc¨ªa-Garc¨ªa %A Eduardo Anitua-Aldecoa %A Rafael Martinez-Conde Llamosas %A Jos¨¦ Manuel Aguirre-Urizar %J Case Reports in Dentistry %D 2013 %I Hindawi Publishing Corporation %R 10.1155/2013/672383 %X The orthokeratinized odontogenic cyst (OOC) is a rare developmental odontogenic cyst that has been considered as a variant of the keratocystic odontogenic tumour (KCOT) until Wright (1981) defined it as a different entity. Surgery is the usual treatment, and recurrence or association with Gorlin-Goltz syndrome has rarely been described. In this report, we presented three cases of this pathology, and we review the principal clinical, histological, radiological, and therapeutic aspects. Case 1. A 73-year-old female presents with a slight swelling on the right mandible, associated with an unilocular well-defined radiolucent lesion. Case 2. A 27-year-old female presents with a painful mandibular swelling associated with an unilocular radiolucent lesion posterior to the 4.8. Case 3. A 61-year-old male was casually detected presents with an unilocular radiolucent lesion distal to the 4.8. Conclusion. The OOC is a specific odontogenic clinicopathological entity that should be differentiated from the KCOT as it presents a completely different biological behaviour. 1. Introduction The orthokeratinized odontogenic cyst (OOC) is a developmental odontogenic cyst relatively rare, arising from the cell rests of the dental lamina [1, 2]. It was first described by Schultz in 1927 [3] as an orthokeratinized variant of the formerly called odontogenic keratocyst, today known as the keratocystic odontogenic tumour. It is not until 1981 that Wright defines this as an independent entity [4]. Since then it has received various designations, such as ¡°orthokeratinized variant of odontogenic keratocyst¡± or ¡°orthokeratinized cyst of the mandible¡±. It is not until 1998 that Li et al. suggest the term ¡°orthokeratinized odontogenic cyst,¡± which is the most accepted at the present time [2, 5]. The OOC occurs predominantly in males between the third and fourth decades, with a mean age of 33.5 years [2, 5]. The lesion is located mainly in the molar region and posterior mandible [1, 2]. These tumours can reach a large size that causes cortical expansion and presents as a swelling, along with pain, although in most cases it can be detected incidentally during a radiographic examination [1, 2]. Radiographically the cyst appears as a well-circumscribed, unilocular, or multilocular radiolucency that occasionally is associated with an unerupted tooth or with the root without causing resorption [1, 6, 7]. Displacement of neighbouring teeth and of the inferior dental canal has been described [5]. The histopathological analysis confirms the diagnosis which shows a cystic cavity lining composed %U http://www.hindawi.com/journals/crid/2013/672383/