%0 Journal Article
%T Incisional Surgical Site Infection after Elective Open Surgery for Colorectal Cancer
%A Kosuke Ishikawa
%A Takaya Kusumi
%A Masao Hosokawa
%A Yasunori Nishida
%A Sosuke Sumikawa
%A Hiroshi Furukawa
%J International Journal of Surgical Oncology
%D 2014
%I Hindawi Publishing Corporation
%R 10.1155/2014/419712
%X Background. The purpose of this study was to clarify the incidence and risk factors for incisional surgical site infections (SSI) in patients undergoing elective open surgery for colorectal cancer. Methods. We conducted prospective surveillance of incisional SSI after elective colorectal resections performed by a single surgeon for a 1-year period. Variables associated with infection, as identified in the literature, were collected and statistically analyzed for their association with incisional SSI development. Results. A total of 224 patients were identified for evaluation. The mean patient age was 67 years, and 120 (55%) were male. Thirty-three (14.7%) patients were diagnosed with incisional SSI. Multivariate analysis suggested that incisional SSI was independently associated with TNM stages III and IV (odds ratio [OR], 2.4) and intraoperative hypotension (OR, 3.4). Conclusions. The incidence of incisional SSI in our cohort was well within values generally reported in the literature. Our data suggest the importance of the maintenance of intraoperative normotension to reduce the development of incisional SSI. 1. Introduction Surgical site infections (SSI) are the most common nosocomial infection in surgical patients, contributing to perioperative morbidity, prolonged postoperative hospital length of stay, and increased hospital costs [1¨C3]. The colorectal surgery has been associated with the highest risk of SSI [1], predominately because of the heavy bacterial load of the colon and rectum. The incidence of incisional SSI following colorectal surgery has been reported to range from 5% to 26% [4¨C8]. Although various risk factors for incisional SSI have been reported [1, 4¨C6], there has been no clear consensus on the risk factors contributing to incisional SSI following colorectal surgery. To clarify the incidence and risk factors for incisional SSI, we conducted prospective surveillance of incisional SSI and analyzed plausible factors in patients undergoing elective open surgery for colorectal cancer, performed by a single surgeon. 2. Materials and Methods 2.1. Subjects This prospective observational study was conducted at Keiyukai Sapporo Hospital from January 1, 2009, to December 31, 2009. All patients undergoing elective laparotomy with colorectal resection for cancer by a single board-certified colon and rectal surgeon (Takaya Kusumi) were registered in this cohort. Patients were excluded if the surgical wound was not closed primarily. Also excluded were patients undergoing laparoscopy or simple ostomy creation or closure with associated wedge or
%U http://www.hindawi.com/journals/ijso/2014/419712/