%0 Journal Article
%T Peritoneal Equilibration Test in Costa Rica: Discrepancies from Other Populations
%A Marta Avellan-Boza
%A Fabio Hern¨¢ndez
%A Allan Ramos-Esquivel
%J International Journal of Nephrology
%D 2014
%I Hindawi Publishing Corporation
%R 10.1155/2014/326163
%X Objective. Continuous Ambulatory Peritoneal Dialysis (CAPD) is a kidney replacement therapy that has been recently incorporated in developing countries. We aim to establish our reference values, to compare them with the original and the Mexican population, and to associate some variables with the type of peritoneal transport. Methods. Thirty peritoneal equilibration tests (PET) were performed. The ratio for D/P creatinine and the D/D0 ratio for glucose were calculated and compared to reference values. We conducted a retrospective analysis to correlate peritoneal transporters with some predictive variables. Results. D/P creatinine ratio at 2 hours, D/D0 glucose ratio at 4 hours, and net ultrafiltrate volume (nUFV) were significantly different from those reported by Twardowski et al. The results documented in the Mexican population only coincide with our results for the D/P creatinine ratio at 4 hours. Any of the studied variables were associated with a specific type of peritoneal transport. Conclusions. Peritoneal permeability among Costa Rican CAPD patients is different from the original population described by Twardowski et al. and from other Latin-American population. This supports the theory that ethnical differences could be responsible for such variations and they validate our statement that each region should possess value references of their own. 1. Introduction In Costa Rica, continuous ambulatory peritoneal dialysis (CAPD) was introduced in the late eighties, initially with few patients as a short-term renal replacement therapy. Currently, social security covers around one hundred fifty adult patients (2/3 of which are men) distributed in four main hospitals around the country. Patients undergoing CAPD exhibit a wide variability in the peritoneal transport of solutes and fluids. Measuring the characteristics of peritoneal membrane transport is important for the characterization of the functional state as for the prescription of the adequate dose of dialysis therapy in an individual fashion [1, 2]. The peritoneal equilibration test (PET) is the most widely used method to characterize and classify the peritoneal transport of patients on dialysis, and their methodology was standardized by Twardowski et al. [2, 3] more than two decades ago. The PET characterizes the peritoneal membrane transport properties by determining the ratio of the creatinine concentration in the dialysate to that in the plasma after a 4£¿h dwell (D/Pc) and has been shown to vary considerably among individuals. However, even if the results are highly consistent in the same
%U http://www.hindawi.com/journals/ijn/2014/326163/