%0 Journal Article %T Effective Assessment of Diabetes Control Using Personal Glucometers (CONTOURLINK, Bayer, Germany; CALLA, Wellion, Austria; LINUS, Agamatrix, USA) %A R. Chlup %A B. Doubravova %A J. Bartek %A J. Zapletalova %A O. Krystynik %A V. Prochazka %J Disease Markers %D 2013 %R 10.1155/2013/702427 %X Aim of this trial was to assess (1) the accuracy and precision of electrochemistry-based glucometers CONTOURLINK, CALLA, and LINUS and (2) the diabetes control using Ambulatory Glycaemic Profiles (AGP) as markers of therapeutic effectiveness. Glucometers and COBAS INTEGRA 400 Plus analyzer were used by one laboratory professional to estimate P-glucose (PG) in 112 out-patients. There were 112 sets of 12 PG estimations analyzed. In each set, means of 3 capillary PG estimations on 3 respective glucometers and on INTEGRA analyzer were calculated. The statistical program SPSS, v. 15, was applied. The mean INTEGRA PG values ranged from 2.7 to 25.3£¿mmol/L. There were strong correlations between mean PG on INTEGRA versus CONTOURLINK, versus CALLA, and versus LINUS; PG deviations from INTEGRA were mostly within the range ¡À15%. Wilcoxon Signed Rank Test revealed differences between CONTOURLINK-INTEGRA and LINUS-INTEGRA; CALLA-INTEGRA showed no difference. SD INTEGRA = 0.061£¿mmol/L, SD CONTOURLINK/SD CALLA/SD LINUS were 0.256/0.290/0.286£¿mmol/L. All patients were trained to perform defined 10-point PG profiles to adapt food, exercise, and insulin doses. The PG differences between all tested glucometers and reference values were in borderline of ISO 15197 but worthy of consideration. AGP are helpful markers of diabetes control. 1. Introduction Fasting and postprandial plasma glucose concentrations (PG) are principal diagnostic markers of diabetes mellitus. Physiological development of PG in the course of day and night is a prerequisite for the optimum physical and intellectual working capacity and prevention of diabetes complications. Therefore, the diabetes treatment is targeting on recovery of glucose homeostasis. Haemoglobin A1c brings information on long-lasting diabetes control. However, in daily life, a simple marker enabling undelayed assessment of various external factors and therapeutic outcomes is needed; ambulatory glycaemic profiles (AGP) with timing and quantity of food, exercise, and insulin dosage are known to be helpful to assess the diabetes control and the effects of various therapeutic and interfering factors [1¨C3]. Since the discovery of insulin by Paulescu in 1921 [4] and after its purification and introduction to human medicine by Banting, Best, Collip, and Mc Leod in 1922 [5], the needs of comfortable estimation of PG concentration are continuously growing [6, 7]. In 1974, the first glucometer (Ames) was introduced into clinical practice. To date, self-monitoring by means of various glucometer-strips systems is widely applied [8¨C11]. Diabetes %U http://www.hindawi.com/journals/dm/2013/702427/