%0 Journal Article
%T C57BL/6N Albino/Agouti Mutant Mice as Embryo Donors for Efficient Germline Transmission of C57BL/6 ES Cells
%A Branko Zevnik
%A Nathalie C. Uyttersprot
%A Ana V. Perez
%A Gerald W. M. Bothe
%A Heidrun Kern
%A Gunther Kauselmann
%J PLOS ONE
%D 2014
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0090570
%X We generated C57BL/6NTac mice carrying a tyrosinase loss-of function mutation and a reversion of the nonagouti locus to agouti. This strain has a high superovulation response, allows visual detection of chimeric coat color contribution of C57BL/6 ES-cells and provides a simplified breeding format that generates black G1 offspring of pure inbred C57BL/6 background in one step, providing the ideal host for genetically manipulated C57BL/6 ES cells.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0090570