%0 Journal Article
%T Risk Factors for Periprosthetic Joint Infection after Total Hip Arthroplasty and Total Knee Arthroplasty in Chinese Patients
%A Chuanlong Wu
%A Xinhua Qu
%A Fengxiang Liu
%A Huiwu Li
%A Yuanqing Mao
%A Zhenan Zhu
%J PLOS ONE
%D 2014
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0095300
%X Purpose The purpose of this hospital-based case每control study was to evaluate the risk factors for periprosthetic joint infection (PJI) of total hip arthroplasty (THA) and total knee arthroplasty (TKA) in Chinese patients. Method From January 2000 to December 2012, 45 patients undergoing THA and TKA who developed PJI were recruited for case subjects; controls were 252 without PJI, matched by year of index for surgery and type of surgery. Conditional logistic regressions were run to compute odds ratios (ORs) and 95% confidence intervals (CIs). Results Demographic factors and comorbid conditions associated with an increased adjusted risk of PJI (in decreasing order of significance) were diabetes (OR = 5.47, 95% CI: 1.77每16.97; p = 0.003), age (65每75 vs. 45每65 years) (OR = 3.36, 95% CI: 1.30每8.69; p = 0.013), BMI (≡28 vs. 18.5每28 kg/m2) (OR = 2.77, 95% CI: 1.20每6.40; p = 0.017), place of residence (rural) (OR = 2.63, 95% CI: 1.13每6.10; p = 0.025) and alcohol abuse (OR = 2.95, 95% CI: 1.06每8.23; p = 0.039). Conclusion Patients with diabetes, older age, BMI of ≡28 kg/m2 and alcohol abuse or living in rural areas, had increased PJI risk. Additional systematic large-scale studies are needed to verify these results.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0095300