%0 Journal Article
%T An Innovative Concept Gel to Prevent Skin Aging
%A Adele Sparavigna
%A Beatrice Tenconi
%A Ileana Deponti
%A Francesco Scarci
%A Maurizio Caserini
%A Federico Mailland
%J Journal of Cosmetics, Dermatological Sciences and Applications
%P 271-280
%@ 2161-4512
%D 2013
%I Scientific Research Publishing
%R 10.4236/jcdsa.2013.34041
%X <p class=\"MsoNormal\">
	<span lang=\"EN-US\"><span style=\"font-family:Verdana;\">The study
aimed to evaluate the instrumental and clinical properties of an innovative gel
formulation for anti-aging treatment. This was an open, non-controlled study, where
the eligible subjects, divided into three subgroups according to age, had to
perform a single dose application of the gel on the face for a short-term
evaluation and a 4-week repeated use, twice a day, for a long-term evaluation.
Instrumental and clinical evaluations had to be performed mono-laterally at the
level of the face (right or left side according to a predisposed randomization
list) in basal conditions (T</span><sub><span style=\"font-family:Verdana;\">0</span></sub><span style=\"font-family:Verdana;\">), 20 minutes after the first dose
application (T</span><sub><span style=\"font-family:Verdana;\">20min</span></sub><span style=\"font-family:Verdana;\">) and after 2 and 4 weeks of treatment (T</span><sub><span style=\"font-family:Verdana;\">2wks</span></sub><span style=\"font-family:Verdana;\"> - T</span><sub><span style=\"font-family:Verdana;\">4wks</span></sub><span style=\"font-family:Verdana;\">). Thirty-three subjects completed the study showing, after
only 20 minutes from the 1</span><sup><span style=\"font-family:Verdana;\">st</span></sup><span style=\"font-family:Verdana;\"> product application, a clinically
important and statistically significant improvement of crow¡¯s feet, skin
dullness clinical score and cutaneous microrelief clinical score (p &lt; 0.05),
after 2 weeks of treatment an improvement of skin tonicity (p &lt; 0.05) and after
4 weeks of treatment having a significant decrease of nasolabial folds clinical
score (p &lt; 0.05). The study showed the great efficacy of an innovative
anti-aging gel in reducing the skin roughness and skin dryness, improving the
skin firmness and, in general, providing a global skin rejuvenation.</span></span> 
</p>
%K Skin
%K Wrinkles
%K Anti-Aging
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=40693