%0 Journal Article
%T A Case of Carbapenem Resistant Non-K1/K2 Serotype <i>Klebsiella pneumoniae</i> Liver Abscess
%A Lucy Cheng
%A Leung Kristopher Siu
%A Tom Chiang
%J Advances in Infectious Diseases
%P 219-222
%@ 2164-2656
%D 2013
%I Scientific Research Publishing
%R 10.4236/aid.2013.33032
%X <p class=\"MsoNormal\">
	<i><span lang=\"EN-US\">Klebsiella pneumoniae</span></i><span lang=\"EN-US\"> liver abscess (KPLA) has been described as an</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">invasive syndrome with extrahepatic
complications. The majority of</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">KPLA </span><span lang=\"EN-US\">is</span><span lang=\"EN-US\"> caused by capsular serotype K1 and K2 isolates. We report a</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">case of carbapenem resistant <i>Klebsiella pneumoniae </i>liver abscess.</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">The patient initially presented with
infected right above</span><span lang=\"EN-US\">-</span><span lang=\"EN-US\">the</span><span lang=\"EN-US\">-</span><span lang=\"EN-US\">knee</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">amputation and was later found with a
large</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">liver abscess.
Initial antimicrobial susceptibility showed</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">carbapenem</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">resistant <i>K. pneumoniae</i></span><i><span lang=\"EN-US\"> </span></i><span lang=\"EN-US\">(CRKP). Further molecular workup
revealed</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">that the isolate
was a less virulent non-K1/K2 serotype, and both <i>rmpA</i> and <i>kfu</i></span><i><span lang=\"EN-US\"> </span></i><span lang=\"EN-US\">genes </span><span lang=\"EN-US\">were </span><span lang=\"EN-US\">negative. The lack of outer membrane porins likely</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">contributed to the carbapenem
resistance.</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">To
our knowledge, this is a first reported case of carbapenem</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">resistant, non-K1/K2 serotype <i>K. pneumoniae</i> liver abscess in the</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">United States.</span>
</p>
%K Liver Abscess
%K &lt
%K i&gt
%K Klebsiella pneumoniae&lt
%K /i&gt
%K Capsular Serotype
%K Carbapenem Resistance
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=36615