%0 Journal Article
%T Photoisomerization of Provitamin D in Hydrogel Matrix
%A I. P. Terenetskaya
%A Yu. M. Samchenko
%A T. N. Orlova
%A N. A. Pasmurceva
%A P. S. Kapinos
%A I. E. Boldeskul
%A Z. R. Ulberg
%J Soft
%P 8-12
%@ 2327-0802
%D 2013
%I Scientific Research Publishing
%R 10.4236/soft.2013.22003
%X Study of interfacial processes between incorporated biomolecules and hydrogel matrix is of primary importance for the application of synthetic hydrogels as biomaterials, sensors, etc. Their hydrophilic nature, however, hampers fat-soluble biomolecule incorporation. We synthesized N-isopropylacrylamide (NIPAAm)- and Acrylamide (AA)-based hydrogels with hydrophilic-lipophilic balance that under specific conditions permit homogeneous incorporation of provitamins D<sub>3</sub>(7-dehydrocholesterol) and D<sub>2</sub>(ergosterol) dissolved in ethanol. Similarity of provitamins D photoisomerization in such hydrogel matrices with the photoreaction in ethanol shows great potential of the novel material for personal dosimetry of biologically active ¡®antirachitic¡¯ UV radiation.
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%K Hydrogels
%K Provitamin D Photoisomerization
%K UV Biodosimeter
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=33784