%0 Journal Article
%T Vectors for gene therapy: A place for DNA transposon
%A Beno£¿t Ch¨¦nais
%J Open Journal of Genetics
%P 1-11
%@ 2162-4461
%D 2013
%I Scientific Research Publishing
%R 10.4236/ojgen.2013.32A1001
%X <p>
	<span style=\"font-size:10.0pt;\">Gene therapy offers
important perspectives in current and future medicine but suffers from
imperfect vectors for the delivery of the therapeutic gene. Most preclinical
and clinical trials have been based on the use of viral vectors, which have
evident advantages but also some serious disadvantages. In the past dec<span>ade the use of DNA transposon-based systems for
gene delivery has emerged as a non-viral alternative. DNA</span> transposon
vector engineering remains largely in a preclinical phase but some interesting
results have been obtained. This mini-review aims to provide the current state
of the art on DNA transposon vectors used in a gene therapy perspective.</span><span style=\"font-size:10.0pt;\"></span> 
</p>
%K Keywords: Transposable Element
%K Gene Delivery
%K Non-Viral Vectors
%K Piggybac
%K Sleeping Beauty
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=33669