%0 Journal Article
%T Assessment of Warm and Cold Ischemia on Functions of the Operated Kidney with <sup>99m</sup>Tc-DMSA in Renal Masses: A Prospective and Randomized Study
%A Abdullah Demirtas
%A Numan Baydilli
%A Nurettin Sahin
%A Oguz Ekmekcioglu
%A Deniz Demirci
%A Atila Tatlisen
%J Open Journal of Urology
%P 62-67
%@ 2160-5629
%D 2013
%I Scientific Research Publishing
%R 10.4236/oju.2013.32012
%X <p class=\"MsoNormal\">
	<b><span lang=\"EN-US\">Objective:</span></b><span lang=\"EN-US\"> To examine the effect of warm and cold ischemia on functions of the
operated kidney in cases with a normal contralateral kidney undergoing nephron
sparing surgery.</span><span lang=\"EN-US\"> </span><b><span lang=\"EN-US\">Methods:</span></b><span lang=\"EN-US\"> This study enrolled 40 patients with a normal contralateral kidney
and without a renal function threatening risk factor, who were operated with
NSS. The patients were randomized at admission. They were divided into 2 equal
groups as warm and cold ischemia. An ice application for 10 minutes was done to
cold ischemia group after clamping renal artery. Renal functions were evaluated
with Technesium<st1:chmetcnv tcsc=\"0\" numbertype=\"1\" negative=\"True\" hasspace=\"False\" sourcevalue=\"99\" unitname=\"m\" w:st=\"on\">-99m</st1:chmetcnv>-Dimercaptosuccinic
Acid (DMSA) and serum creatinine at the preoperative and postoperative (day 1,
day 15, month 6, and month 12) period. Statistical analysis was done with Mann
Whitney U test, Wilcoxon Signed Rank test, and Fredman test. A p value below
0.05 was considered statistically significant.</span><span lang=\"EN-US\"> </span><b><span lang=\"EN-US\">Results:</span></b><span lang=\"EN-US\"> There were no significant dif</span><span lang=\"EN-US\">ferences
between the groups in terms of age, body mass index, ischemia time, tumor size,
amount of hemorrhage, and procedure time. Both groups had a significantly
higher DMSA uptake at the preoperative period compared with the postoperative
period (postoperative day 1, day 15, month 6, and month 12) (p</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">&lt;</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\">0</span><span lang=\"EN-US\">.</span><span lang=\"EN-US\">001).
However, both groups had similar DMSA uptake results at the postoperative
period. Preoperative and postoperative creatinine levels were not significantly
different from each other in both groups.</span><span lang=\"EN-US\"> </span><b><span lang=\"EN-US\">Conclusion:</span></b><span lang=\"EN-US\"> Based on tumor localization,
nephron sparing surgery without use of superficial cooling appears as a viable
option for small renal masses.</span><span lang=\"EN-US\"><o:p></o:p></span> 
</p>
%K Cold Ischemia Times
%K Nephron Sparing Surgery
%K Renal Cancer
%K Technetium-99m-Dimercaptosuccinic Acid
%K Warm Ischemia Times
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=31321