%0 Journal Article %T Solid State Bioconversion for Producing Common Bean (<i>Phaseolus</i> <i>vulgaris</i> L.) Functional Flour with High Antioxidant Activity and Antihypertensive Potential %A Maria Lilia Guzm¨¢n-Uriarte %A Luis Mart¨ªn S¨¢nchez-Maga£¿a %A Graciela Yaneth Angulo-Meza %A Edith Oliva Cuevas-Rodr¨ªguez %A Roberto Guti¨¦rrez-Dorado %A Saraid Mora-Roch¨ªn %A Jorge Mil¨¢n-Carrillo %A Angel Valdez-Ortiz %A Cuauht¨¦moc Reyes-Moreno %J Food and Nutrition Sciences %P 480-490 %@ 2157-9458 %D 2013 %I Scientific Research Publishing %R 10.4236/fns.2013.44061 %X

The main objective of this investigation was to study the time effect during solid state bioconversion (SSB) on total phenolics content (TPC) and antioxidant activity (AoxA) of common beans to improve antihypertensive functionality. Cooked cotyledons of dehulled common beans were inoculated with a suspension of R. oligosporus NRRL 2710 (1 ¡Á 106 spores/mL), and incubated at 35¡æ for times of 24, 36, 48, 60, 72, 84, 96 and 108 h (after 108 h the cotyledons showed off odor). Flours from bioprocessed dehulled common bean from each incubation time were blended with their corresponding milled seed coats. The best time for producing bioprocessed common bean (added with seed coats) functional flour with the highest AoxA (ORAC value = 17,468 ¦Ìmol Trolox equivalents (TE)/100 gsample, dw; ABTS value = 13,505 ¦Ìmol TE/100 gsample, dw) was 108 h. The SSB process substantially increased TPC and total hydrophilic AoxA and antihypertensive potential of common beans in 2.24, 2.45 - 2.73 and 6769 times, respectively. Proteins hydrolyzates from unprocessed whole and bioprocessed (108 h) common beans had IC50 [concentration needed to inhibit 50% the activity of angiotensin converting enzyme (ACE)] of 79.2 and 0.0117 ¦Ìg/mL, respectively. The SSB is an efective strategy to improve the TPC of common beans for enhanced functionality with improved antioxidant activity and antihypertensive potential.

%K Solid State Bioconversion %K Common Bean Functional Flour %K Antioxidant Activity %K Antihypertensive Activity %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=30346