%0 Journal Article
%T Asymptomatic T-cell large granular lymphocyte leukemia with an unusual immunophenotype
%A Panagiota K. Petsa
%A Achilleas Karamoutsios
%A Lefkothea Dova
%A Leonidas Benetatos
%J Clinics and Practice
%D 2012
%I PAGEPress Publications
%R 10.4081/cp.2012.e68
%X T-cell large granular lymphocyte (T-LGL) leukemia represents a clonal proliferation of cytotoxic T-cells which etiology has not been entirely elucidated. However, CD4+, CD4¨C,CD8¨C, CD4+, CD8+ cases have been described. The disease is usually characterized by cytopenias and a modest lymphocytosis. The majority of patients with T-LGL leukemia remains asymptomatic for a long period and will require treatment later during the course of their disease. Hereby we describe a case of T-LGL leukemia diagnosed by flow cytometry, which presented indolent course and required no treatment so far.
%K large granular lymphocytes
%K T-LGL leukemia
%K T cell receptor
%K flow cytometry.
%U http://www.clinicsandpractice.org/index.php/cp/article/view/320