%0 Journal Article
%T Synthesis and structure of vanillin azomethines
%A Sandra S. Konstantinovi£¿
%A Budimir V. Konstantinovi£¿
%A Jasmina M. Jovanovi£¿
%J Chemical Industry and Chemical Engineering Quarterly
%D 2009
%I Association of the Chemical Engineers
%X Vanillin is most prominent as the principal flavor and aroma compound in vanilla. Vanillin has been used as a chemical intermediate in the production of pharmaceuticals and other fine chemicals.The two intermediates, assigned as intermediates I and II, were prepared by using vanillin and 1-butylbromide or 2-chloroacetic acid, respectively. The condensation of intermediates with 2,3- -diaminopyridine gave azomethines. Their structure was established by using elemental microanalysis, as well as UV/Vis, FTIR and 1H-NMR spectra. Synthesized compounds were tested for their antifungal activity against Candida albicans, Candida lipolytica and Sacharomyces cerevisiae.
%K Vanillin is most prominent as the principal flavor and aroma compound in vanilla. Vanillin has been used as a chemical intermediate in the production of pharmaceuticals and other fine chemicals.The two intermediates
%K assigned as intermediates I and II
%K were prepared by using vanillin and 1-butylbromide or 2-chloroacetic acid
%K respectively. The condensation of intermediates with 2
%K 3- -diaminopyridine gave azomethines. Their structure was established by using elemental microanalysis
%K as well as UV/Vis
%U http://www.ache.org.rs/CICEQ/2009/No4/CICEQ_Vol15_%20No4_pp279-281_Oct-Dec_2009.pdf