%0 Journal Article
%T Update on triple therapy for eradication of Helicobacter pylori: current status of the art
%A Urgesi R
%A Cianci R
%A Riccioni ME
%J Clinical and Experimental Gastroenterology
%D 2012
%I Dove Medical Press
%X Riccardo Urgesi,1 Rossella Cianci,2 Maria Elena Riccioni31Gastroenterology and Endoscopy Unit, Viterbo, 2Institute of Internal Medicine, Catholic University of Rome, 3Digestive Endoscopy Unit, Catholic University of Rome, Rome, ItalyAbstract: With the rising prevalence of antimicrobial resistance, the treatment success of standard triple therapy has recently declined to unacceptable levels (ie, 80% or less). Following the failure of conventional triple therapy, novel eradication regimens have been developed including sequential therapy, concomitant quadruple therapy, hybrid (dual-concomitant) therapy, bismuth-containing quadruple therapy, and a therapy with administration of N-acetylcysteine before a culture-guided antibiotic regimen. This article reviews the literature published on Helicobacter pylori eradication in the last year, focusing on the development of alternative strategies for first-, second-, and third-line rescue therapy for the eradication of H. pylori.Keywords: sequential therapy, quadruple therapy, concomitant therapy, hybrid therapy, N-acetylcysteine
%U http://www.dovepress.com/update-on-triple-therapy-for-eradication-of-helicobacter-pylori-curren-a11023