%0 Journal Article
%T Bead-Selected Antitumor Genetic Cell Vaccines
%A Herrero MJ
%A Botella R
%A Alg¨¢s R
%A Marco FM
%J Clinical Medicine : Oncology
%D 2008
%I 
%X Cancer vaccines have always been in the scope of gene therapy research. One of the most successful approaches has been working with genetically modified tumor cells. However, to become a clinical reality, tumor cells must suffer a long and risky process from the extraction from the patient to the reimplantation as a vaccine. In this work, we explain our group¡¯s approach to reduce the cell number required to achieve an immune response against a melanoma murine model, employing bead-selected B16 tumor cells expressing GM-CSF and B7.2.
%K cancer vaccines
%K gene therapy
%K bead selection
%K GM-CSF
%K B7.2
%U http://la-press.com/article.php?article_id=644