%0 Journal Article
%T SHELL-NANOSTRUCTURED MATERIALS FOR BIOPHARMACY AND BIOMEDICINE
%A D. Lj. Mirjani£¿
%A A. J. £¿etraj£¿i£¿ Tomi£¿
%A P. £¿etraj£¿i£¿
%J Contemporary Materials
%D 2011
%I Academy of Sciences and Arts of Republic of Srpska
%X Ba-sed on our re-se-arch in ul-trat-hin crystal struc-tu-res per-for-med so far, su-per-lat-ti-ces, Q-wi-res and Q-dots, we will con-si-der the ma-te-ri-als that can act as car-ri-ers for me-di-ci-nes and tag-ged sub-stan-ces. For this pur-po-se we esta-blis-hed a shell-mo-del of ul-trat-hin mo-le-cu-lar crystals and in-ve-sti-ga-ted the-ir di-e-lec-tric, par-ti-cu-larly op-tic cha-rac-te-ri-stics. We con-duc-ted this re-se-arch with the help of two-ti-me de-pen-dent Green's fun-ction met-hod, adju-sted to ul-trat-hin crystal-li-ne struc-tu-re analysis. It is shown that spe-ci-fic re-so-nant ab-sorp-tion li-nes ap-pe-ar in the-se struc-tu-res, the num-ber of which de-pends on crystal layers po-si-tion and on va-lu-es of pa-ra-me-ters on shell-struc-tu-re bo-un-dary sur-fa-ces. The ab-sorp-tion of elec-tro-mag-ne-tic ra-di-a-tion dec-li-nes in in-fra-red part and its de-tec-tion is a re-la-ti-vely easy pro-cess.In this pa-per we will analyze ap-pli-ca-tion of na-no-ma-te-ri-als in bi-o-me-di-ci-ne, that is to say we will pre-sent the re-cent ac-com-plis-hments in ba-sic and cli-ni-cal na-no-me-di-ci-ne. Ac-hi-e-ving full po-ten-tial of na-no-me-di-ci-ne may be years of even de-ca-des away, ho-we-ver, po-ten-tial advan-ces in drug de-li-very, di-ag-no-sis, and de-ve-lop-ment of na-no-tec-hno-logy-re-la-ted drugs start to chan-ge the landsca-pe of me-di-ci-ne. Si-te-spe-ci-fic tar-ge-ted drug de-li-very (ma-de pos-si-ble by the ava-i-la-bi-lity of uni-que de-li-very plat-forms, such as den-dri-mers, na-no-par-tic-les and na-no-li-po-so-mes) and per-so-na-li-zed me-di-ci-ne (re-sult of the advan-ce in phar-ma-co-ge-ne-tics) are just a few con-cepts on the ho-ri-zon of re-se-arch. In this pa-per, espe-ci-ally, we ha-ve analyzed the chan-ges in ba-sic physi-cal pro-per-ti-es of sphe-ri-cal-sha-ped na-no-par-tic-les that can be ma-de in se-ve-ral (na-no)layers and ha-ve, at the sa-me ti-me, mul-ti-ple ap-pli-ca-ti-ons in me-di-ci-ne.
%K shell model
%K nanomaterials
%K biopharmacy
%K nanomedicine.
%U http://www.savremenimaterijali.info/sajt/doc/file/casopisi/2_1/5_mirjanic.pdf