%0 Journal Article
%T Prevention of Congenital Transmission of Malaria in Sub-Saharan African Countries: Challenges and Implications for Health System Strengthening
%A Kayode O. Osungbade
%A Olubunmi O. Oladunjoye
%J Journal of Tropical Medicine
%D 2012
%I Hindawi Publishing Corporation
%R 10.1155/2012/648456
%X Objectives. Review of burden of congenital transmission of malaria, challenges of preventive measures, and implications for health system strengthening in sub-Saharan Africa. Methods. Literature from Pubmed (MEDLINE), Biomed central, Google Scholar, and Cochrane Database were reviewed. Results. The prevalence of congenital malaria in sub-Saharan Africa ranges from 0 to 23%. Diagnosis and existing preventive measures are constantly hindered by weak health systems and sociocultural issues. WHO strategic framework for prevention: intermittent preventive therapy (IPT), insecticide-treated nets (ITNs), and case management of malaria illness and anaemia remain highly promising; though, specific interventions are required to strengthen the health systems in order to improve the effectiveness of these measures. Conclusion. Congenital malaria remains a public health burden in sub-Saharan Africa. Overcoming the challenges of the preventive measures hinges on the ability of national governments and development partners in responding to the weak health systems. 1. Introduction Malaria remains a significant burden in sub-Saharan Africa as it continues to be the leading cause of infant morbidity and mortality in Africa. It is believed that malaria contributes up to about 25% of infant mortality in Nigeria [1]. Furthermore, in areas of Africa with stable transmission, Plasmodium falciparum infection during pregnancy is estimated to cause as many as 10,000 maternal deaths each year, 8% to 14% of all low birth weight babies, and 3% to 8% of all infant deaths [2]. Thus, malaria burden, if not reduced, poses a threat to the attainment of the Millennium Development Goals 4 and 6. Congenital malaria is defined as malaria in a newborn or infant, transmitted from the mother [3]. Congenital malaria is generally defined as malaria acquired by the fetus or newborn directly from the mother, either in utero or during delivery [4]. It is also defined as the presence of malarial parasites in the peripheral smear of the newborn from twenty four hours to seven days of life [5]. Malaria is considered to be congenital in the neonate when asexual parasites are detected in the peripheral blood within the first week of life [6, 7]. Congenital malaria was thought to be rare in developing countries [8, 9]. This might be due to a number of reasons. Firstly, the protective effect of the foetal haemoglobin (HbF) in a newborn is expected to exert its influence during the immediate neonatal period [10, 11]. Secondly, local health facilities in resource-limited settings often lack the capacity to
%U http://www.hindawi.com/journals/jtm/2012/648456/