%0 Journal Article
%T Role of cathepsin A and cathepsin C in the regulation of glycosidase activity
%A Alina Minarowska
%A £¿ukasz Minarowski
%A Alicja Karwowska
%A Anna Justyna Milewska
%J Folia Histochemica et Cytobiologica
%D 2012
%I Polish Histochemical and Cytochemical Society
%R 10.5603/18692
%X Increased tissue activity of cathepsin A and cathepsin C can be observed in many pathological conditions. It is associated with an enhanced degradation of glycosaminoglycans, proteoglycans, and glycoproteins, and results in their decreased tissue content. Cathepsin C releases the glycosidases from complexes formed with cathepsin A, and reinstates their activity. In this review a current state of knowledge is presented concerning the regulation of selected glycosidases activity by cathepsin A (EC 3.4.16.1) and C (EC 3.4.14.1).
%K cathepsin A
%K lysosomal carboxypeptidase A
%K cathepsin C
%K dipeptydyl peptidase I
%K glycosidase activity
%U http://czasopisma.viamedica.pl/fhc/article/view/18692