%0 Journal Article %T 10-valent Protein D Conjugated Pneumococcal Vaccine (PHID-CV,Synflorix,GSK) %A Nuran Salman %J Cocuk Enfeksiyon Dergisi %D 2010 %I Aves Yayincilik %X S.pneumoniae is the most important pathogen causing invasive disease such as meningitis and sepsis. Pneumococcal conjugate vaccines are vaccines designed to protect children from invasive diseases. Glaxo Smith Kline¡¯s novel 10-valent pneumococcal conjugate vaccine (PH D-CV) includes serotypes 1.5 and 7F which are not in the 7-valent vaccine (Prevenar). Nontypeable H. influenzae (NTH ) is one of the two major pathogens that cause acute bacterial otitis media. PH D-CV has a new carrier, protein D, derived from NTH that potentially offers protection against NTH infection by virtue of the protein D carrier protein. This carrier also minimises the risk of interference with co-administered vaccines.Various studies demonstrated the immunogenicity (by EL SA and OPA), safety and tolerability of PH D-CV. %K S.penumoniae %K pneumoccocal conjugate vaccines %K vaccination %U http://www.cocukenfeksiyon.org/yazilar.asp?yaziid=418&sayiid=