%0 Journal Article
%T Novel approach to bis(indolyl)methanes using nickel nanoparticles as a reusable catalyst under solvent-free conditions
%A Olyaei Abolfazl
%A Vaziri Mohsen
%A Razeghi Reza
%A Bahareh Shams
%J Journal of the Serbian Chemical Society
%D 2013
%I Serbian Chemical Society
%R 10.2298/jsc120506076o
%X A nanosized Nickel as catalyst has been developed for the electrophilic substitution reactions of indole with variousaromatic aldehydes under solvent-free conditions to afford the corresponding bis(indolyl)methanes in high to excellent yields. The described method has promising features such as no hazardous organic solvents or catalysts, short reaction time, high product yields, simple work-up procedure, reusable catalyst and easy product separation without further purification with column chromatography.
%K indole
%K aldehyde
%K electrophilic substitution
%K Ni
%U http://www.doiserbia.nb.rs/img/doi/0352-5139/2013/0352-51391200076O.pdf