%0 Journal Article
%T Spectrophotometric determination of fluocortolone in tablets using 1,4-dihydrazinophthalazine
%A OLIVERA CUDINA
%A SOTE VLADIMIROV
%A DOBRILA ZIVANOV-STAKIC
%A DANICA AGBABA
%J Journal of the Serbian Chemical Society
%D 2000
%I Serbian Chemical Society
%X The proposed method for the determination of fluocortolone is based on the formation of a stable, yellow coloured hydrazone product with 1,4-dihydrazinophthalazine as the reagent. Heating at 85¡ãC for 2 h was found to be necessary to ensure optimal hydrazone formation in acidified 1-propanol as the solvent. The detection limit was 1.2 ¦Ìg/ml. This method when applied for the determination of fluocortolone in pharmaceutical formulations gave precise and reproducible results.
%K fluocortolone
%K 1
%K 4-dihydrazinophthalazine
%K tablets
%K spectrophotometry
%U http://www.shd.org.yu/HtDocs/SHD/Vol65/No9-Pdf/JSCS9-05.pdf