%0 Journal Article
%T Influence of cumulus cell coculture and cumulus-aided embryo transfer on embryonic development and pregnancy rates
%A Nalan Cihangir
%A H¨¹zeyin G£¿rkemli
%A Suna £¿zdemir
%A Murat Aktan
%J Journal of the Turkish-German Gynecological Association
%D 2010
%I Aves Yayincilik
%X Objective: In this study, we aimed to evaluate the influence of autologous cumulus oocyte complex (COC) coculture on embryonic development and quality, and investigate the implantation and pregnancy rates after cumulus-aided embryo transfer in the ICSI-ET cycles.Material and Methods: Ninety five consecutive infertile women undergoing their first cycle of IVF teratment were included in the study. The cases were divided into two groups. Group 1 consisted of 48 women undergoing ICSI, along with autologous cumulus embryo coculture and cumulus-aided emryo transfer. Group 2 comprised 47 consecutive patients who consented to undergo ICSI and in whom autologous cumulus embryo coculture and cumulus-aided embryo transfer were not performed. Implantation and pregnancy rates were compared between the two groups. Results: The demographic data and controlled ovarian hyperstimulation parameters were similar in the two groups. The fertilization and cleavage rates were found to be higher in group 1 when compared with group 2 (p=0.03 and 0.001, respectively). There were no statistical significant differences for the implantation and clinical pregnancy rates between the two groups.Conclusion: Usage of autologous COCs as coculture may improve fertilization and cleavage rates. However, cumulus-aided embryo transfer does not produce an increase in implantation and pregnancy rates.
%K Coculture
%K Cumulus cells
%K ICSI-embryo transfer
%K Pregnancy rate
%U http://www.journalagent.com/z4/download_fulltext.asp?pdir=jtgga&plng=eng&un=JTGGA-53386