%0 Journal Article
%T PRELIMINARY INVESTIGATION ON ANTIPYRETIC ACTIVITY OF CUSCUTA REFLEXA IN RATS
%A Sanjib Bhattacharya
%A Bodhisattva Roy
%J Journal of Advanced Pharmaceutical Technology & Research
%D 2010
%I Medknow Publications
%X In present study, the antipyretic activity of aqueous and ethanol extracts fromCuscuta reflexa Roxb. (Cuscutaceae) was evaluated using BrewerĄ¯s yeast inducedpyrexia in rats. Both the extracts at 200 and 400 mg/kg body weight dose significantly (p< 0.05) reduced the increased rectal temperature. The extracts started reducing theelevated rectal temperature after 3 h of treatment in a dose related manner. At the dose of400 mg/kg body weight the aqueous and ethanol extract reduced 79 % and 83.8 %respectively of the elevated rectal temperature as compared to reference drug paracetamol(96.5 %) after 6 h of treatment. It was therefore concluded that both the extracts of C.reflexa demonstrated antipyretic activity, the ethanol extract was found to be slightlypotent than the aqueous extract.
%K Antipyretic
%K BrewerĄ¯s yeast
%K Cuscuta reflexa
%K phytochemical analysis
%K prostaglandin
%U http://122.168.195.169/Online%20Admission/CourseInstr.aspx?STS=4&MID=68&Title=Preliminary%20investigation%20on%20antipyretic%20activity%20of%20Cuscuta%20reflexa%20in%20rats